I finally got my hands on a ESU LokSound 5XL large scale decoder for testing. So far, it works fine with my receiver, no issues.
Many people rave about the ESU Lok series, but I really don’t see why. It costs about $30 more than it’s competitors, the TCS 501 and the Soundtraxx TSU4400 and it has to be programmed before it will make any sounds. To program it you need a $130 unit unless you get it pre-programmed by the retailer. Physically, the board is ok, a bit wider than the other but not bad. The screw terminals are kinda small, I just did have a screwdriver that would fit. On the plus side, the sound is quite good, motor control is smooth and it has many many programming options. It will also support 4 servos if you need something physical.